Genomics

Teacher

Oplong

Free

COURSE DESCRIPTION

Deoxyribonucleic acid (DNA) is the chemical compound that contains the instructions needed to develop and direct the activities of nearly all living organisms. DNA molecules are made of two twisting, paired strands, often referred to as a double helix

An organism’s complete set of DNA is called its genome. Virtually every single cell in the body contains a complete copy of the approximately 3 billion DNA base pairs, or letters, that make up the human genome.

With its four-letter language, DNA contains the information needed to build the entire human body. A gene traditionally refers to the unit of DNA that carries the instructions for making a specific protein or set of proteins. Each of the estimated 20,000 to 25,000 genes in the human genome codes for an average of three proteins.

COURSE CONTENT

General aspects of Genomics
Fundamentals of cancer genomics
To describe how genomic information is stored
To outline different types of chromosomal and genetic variants
To explain patterns of genomic evolution of cancer
To outline basis mutation signature profiling
To define tumor mutation burden
To describe consequences of misattribution of pathogenicity to germline genetic variants